@article{mbs:/content/journal/micro/10.1099/00221287-42-2-219, author = "CAIN, R. B.", title = "Utilization of Anthranilic and Nitrobenzoic Acids by Nocardia Opaca and a Flavobacterium", journal= "Microbiology", year = "1966", volume = "42", number = "2", pages = "219-235", doi = "https://doi.org/10.1099/00221287-42-2-219", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-42-2-219", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "SUMMARY: Anthranilic and o-nitrobenzoic acids act as mutual inhibitors of both growth and substrate oxidation for Nocardia opaca and a flavobacterium which can utilize either substance as sole source of carbon, nitrogen and energy. Growth of the former bacterium on anthranilate induced, apparently simultaneously, both the transport system for anthranilate uptake and the enzymic mechanism necessary for its complete oxidation to CO2 and NH3. Among the enzymes induced by anthranilate was the complete sequence that oxidizes catechol to β-oxoadipate; this was absent from organisms grown in fumarate or glucose media. The properties of the first enzyme in this sequence, a catechol-1, 2-oxygenase, differ in several features from those of the same enzyme induced in this bacterium by growth on o-nitrobenzoic acid.", }