1887

Abstract

SUMMARY: Three strains of foot-and-mouth disease virus of type SAT 1 were propagated serially in cultures of pig kidney cells in the presence of gradually increased concentrations of specific antiserum. All showed an increase in their ability to multiply in the presence of the serum. With two of the strains, complement-fixation tests revealed that propagation under these conditions was associated with modification of antigenic structure, but antigenic differences were detected later than changes in the ability of all strains to multiply in the presence of antiserum. Processes of this nature may possibly result from similar interactions of virus and antibody in host populations.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-41-1-135
1965-10-01
2019-10-19
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-41-1-135
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error