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A logarithmic-phase culture of Escherichia coli strain 15 t – a – u –, in which protein and RNA syntheses were inhibited for 90min. by withdrawal of arginine and uracil, was compared with a culture grown with all required nutrients present until 90–120 min. after the end of exponential increase in extinction (early stationary phase). The two cultures were indistinguishable by tests of radiation (ultraviolet, gamma) sensitivity, growth kinetics and morphology. It is concluded that the interruption of protein and RNA syntheses during active logarithmic growth forced the culture into the stationary phase.
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