1887

Abstract

SUMMARY

The hypocholesteraemic compounds benzmalecene and triparanol inhibited multiplication of certain bacteria (especially Gram-positive organisms), protozoa, algae and ascomycetes but not other higher fungi. Oleic acid (or methyl oleate) annulled the inhibition in bacteria, algae, protozoa and a yeast.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-39-3-367
1965-06-01
2024-12-08
Loading full text...

Full text loading...

/deliver/fulltext/micro/39/3/mic-39-3-367.html?itemId=/content/journal/micro/10.1099/00221287-39-3-367&mimeType=html&fmt=ahah

References

  1. Aaronson S. 1964a; Inhibition of respiration in a flagellate protozoon by hypochole-sterolemic drugs. Nature, Lond 202:1355
    [Google Scholar]
  2. Aaronson S. 1964b; A role for a sterol and a sterol precursor in the bacterium Rhodopseudomonas palustris . J. gen. Microbiol 37:225
    [Google Scholar]
  3. Aaronson S., Bensky B., Shifrine M., Baker H. 1962; Effect of hypochole-steremic agents on protozoa. Proc. Soc. exp. Biol., Med 109130
    [Google Scholar]
  4. Achor R. W. P., Christensen N. A., Berge K. G., Mason H. L. 1963; Treatment of hypercholesteremia with triparanol and comparison with nicotinic acid. Proc. Staff Meetings Mayo Clin 3832
    [Google Scholar]
  5. Bergh A. K., Webb S. J., McArthur C. S. 1964; Bacterial lipids and the Gram staining reaction. Canad. J. Biochem 42:1141
    [Google Scholar]
  6. Furman R. H., Robinson C. W. Jr 1961; Hypocholesterolemic agents. Med. Clin. N. Amer 45:935
    [Google Scholar]
  7. Garattini S., Paoletti R., Bizzi L., Grossi E., Vertua R. 1961; A comparative evaluation of hypocholesteremizing drugs on several tests. Drugs affecting Lipid Metabolism144–157 Garattini S., Paoletti R. Amsterdam: Elsevier Publishing Co;
    [Google Scholar]
  8. Holmes W. L., Di Tullio N. W. 1962; Inhibitors of cholesterol biosynthesis which act at or beyond the mevalonic acid stage. Amer. J. clin. Nutrition 10:310
    [Google Scholar]
  9. Roe D. A. 1964; Cutaneous effects of hypocholesteremic agents. N.Y. St. J. Med 64:2559
    [Google Scholar]
  10. Salton M. R. J. 1960; Surface layers of the bacterial cell. The Bacteria I97–151 Gunsalus I. C., Stanier R. Y. New York: Academic Press Inc;
    [Google Scholar]
  11. Steinberg D. 1962; Chemotherapeutic control of serum lipid levels. Trans. N.Y. Acad. Sci 24:704
    [Google Scholar]
/content/journal/micro/10.1099/00221287-39-3-367
Loading
/content/journal/micro/10.1099/00221287-39-3-367
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error