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SUMMARY: Some characteristics of adenine inhibition of the rate of sorocarp formation by Dictyostelium discoideum are described. As little as 1·25 × 10−3 M-adenine was markedly inhibitory. All of the stimulants tested (histidine, glucose, Mg2+, K+, PO4 3−, Na+) were capable of stimulating the rate of fructification even in the presence of adenine, although to a lesser extent. It is concluded that the inhibition by adenine and the stimulation by the other materials listed are independent phenomena.
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