1887

Abstract

Summary: A new bacteriocin, megacin C, was recognized in certain strains of ; it was initially observed as the agent responsible for killing sensitive organisms in mixed culture. The bacteriocin was liberated during growth of cultures; but later, after reaching a maximum value, it disappeared from the culture media. Megacin C was produced by strains already known to produce another bacteriocin, megacin A. The activity spectra of the two megacins differed markedly and non-megacin A ( ) mutants still produced megacin C. A preliminary grouping of megacin types is proposed. Megacin A is comparable to the original megacin first studied by Ivánovics & Alföldi (1954). Megacin A produced inhibition zones surrounding colonies on solid medium but its formation in liquid medium required induction with ultraviolet (u.v.) radiation. Megacin B, whose activity spectra differed from those of megacins A and C, can be detected only on a solid medium; it is not formed in liquid culture even after u.v.-irradiation. Megacin C can be detected only on a particular solid medium and its formation in liquid media is not induced by u.v.-irradiation.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-35-2-271
1964-05-01
2019-10-21
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-35-2-271
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error