1887

Abstract

Summary: A new bacteriocin, megacin C, was recognized in certain strains of ; it was initially observed as the agent responsible for killing sensitive organisms in mixed culture. The bacteriocin was liberated during growth of cultures; but later, after reaching a maximum value, it disappeared from the culture media. Megacin C was produced by strains already known to produce another bacteriocin, megacin A. The activity spectra of the two megacins differed markedly and non-megacin A ( ) mutants still produced megacin C. A preliminary grouping of megacin types is proposed. Megacin A is comparable to the original megacin first studied by Ivánovics & Alföldi (1954). Megacin A produced inhibition zones surrounding colonies on solid medium but its formation in liquid medium required induction with ultraviolet (u.v.) radiation. Megacin B, whose activity spectra differed from those of megacins A and C, can be detected only on a solid medium; it is not formed in liquid culture even after u.v.-irradiation. Megacin C can be detected only on a particular solid medium and its formation in liquid media is not induced by u.v.-irradiation.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-35-2-271
1964-05-01
2024-12-09
Loading full text...

Full text loading...

/deliver/fulltext/micro/35/2/mic-35-2-271.html?itemId=/content/journal/micro/10.1099/00221287-35-2-271&mimeType=html&fmt=ahah

References

  1. Alföldi L. 1958; La production induite de mégacine en milieu synthétique.. Ann. Inst. Pasteur 94:474
    [Google Scholar]
  2. Alföldi L., Jacob F., Wollman E. 1957; Zygose létale dans des croisements entre souches colicinogènes et non colicinogènes d’Escherichia coli. . C.r. hebd. Séanc. Acad. Sci., Paris 224:2974
    [Google Scholar]
  3. Barry G. T., Everhart D. L., Graham M. 1963; Colicine A.. Nature, Land. 198:213
    [Google Scholar]
  4. Burrows T. W., Smith D. A. 1962; Bacteriophage and bacteriocin investigations with Pasteurella pestis and other bacteria.. Nature, Land. 193:397
    [Google Scholar]
  5. Fredericq P. 1953; Colicines et bactériophages.. Ann. Inst. Pasteur 84:294
    [Google Scholar]
  6. Fredericq P. 1954; Induction de la production de colicines par irradiation ultraviolette de souches colicinogènes d’Escherichia coli. . C.r. Séanc. Soc. Biol. 148:1276
    [Google Scholar]
  7. Fredericq P. 1955; Induction de la production de colicines et de bactériophages par irradiation ultraviolette de souches colicinogènes et lysogenes d’Escherichia coli. . C.r. Séanc. Soc. Biol. 149:2028
    [Google Scholar]
  8. Fredericq P. 1957; Colicins.. A. Rev. Microbiol. 11:7
    [Google Scholar]
  9. Fredericq P., Betz-Bareau M. 1953a; Transfert génétique de la propriété de produire un antibiotique.. C.r. Séanc. Soc. Biol. 147:1653
    [Google Scholar]
  10. Fredericq P., Betz-Bareau M. 1953b; Transfert génétique de la propriété coli-cinogéne en rapport avec la polarité F des parents.. C.r. Séanc. Soc. Biol. 147:2043
    [Google Scholar]
  11. Fredericq P., Betz-Bareau M. 1956; Influence de diverses proprietes colicinogénes sur la fertilité d’Escherichia coli.. C.r. Séanc. Soc. Biol. 150:615
    [Google Scholar]
  12. Goebel W. F., Barry G. T. 1958; Colicine K. II. The preparation and properties of a substance having colicine K activity.. J. exp. Med. 107:185
    [Google Scholar]
  13. Hamon Y., Peron Y. 1963; Éude du pouvoir bacteriocinogéne dans le genre Listeria. II. Individualité et classification des bactériocines en cause.. Ann. Inst. Pasteur 104:55
    [Google Scholar]
  14. Holland I. B. 1961; The purification and properties of megacin, a bacteriocin from Bacillus megaterium.. Biochem. J. 78:641
    [Google Scholar]
  15. Holland I. B. 1962; Further observations on the properties of megacin, a bacteriocin formed by Bacillus megaterium.. J. gen. Microbiol. 29:603
    [Google Scholar]
  16. Holland I. B. 1963; Effect of a bacteriocin preparation (megacin C) on DNA synthesis in Bacillus megaterium.. Biochem. biophys. Res. Commun. 13:246
    [Google Scholar]
  17. Holland I. B., Roberts C. F. 1963; A search for the transmission of megaeinogenic factors in Bacillus megaterium.. J. gen. Microbiol. 31:xi
    [Google Scholar]
  18. Hutton J. J., Goebel W. F. 1961; Colicine V.. Proc. not. Acad. Sci., Wash. 47:1498
    [Google Scholar]
  19. Ivánovics G. 1962; Bacteriocins and bacteriocin-like substances.. Bact. Rev. 26:108
    [Google Scholar]
  20. Ivánovics G., Alföldi L. 1954; A new antibacterial principle: megacine.. Nature, Land. 174:465
    [Google Scholar]
  21. Ivánovics G., Alföldi L. 1955; Observations on lysogenesis in Bacillus megaterium and on megacine, the antibacterial principle of this bacillus species.. Acta microbiol. hung. 2:275
    [Google Scholar]
  22. Ivánovics G., Alföldi L. 1957; Bacteriocinogenesis in Bacillus megaterium.. J. gen. Microbiol. 16:522
    [Google Scholar]
  23. Ivánovics G., Nagy E. 1958; Heriditary aberrancy in growth of some Bacillus megaterium strains.. J. gen. Microbiol. 19:407
    [Google Scholar]
  24. Ivánovics G., Alföldi L., Nagy E. 1959a; Mode of action of megacin.. J. gen. Microbiol. 21:51
    [Google Scholar]
  25. Ivánovics G., Alföldi L., Nagy E. 1959b; Masked provirus in Bacillus megaterium strains.. Acta virol., Prague 3:23
    [Google Scholar]
  26. Jacob F., Lwoff A., Siminovitch L., Wollman E. 1953; Définition de quelques termes relatifs à la lysogénie.. Ann. Inst. Pasteur 84:222
    [Google Scholar]
  27. Jacob F., Schaeffer P., Wollman E. L. 1960; Microbial genetics.. Symp. Soc. gen. Microbiol. 10:67
    [Google Scholar]
  28. Jacob F., Wollman E. L. 1961 Sexuality and the Genetics of Bacteria93 New York: Academic Press;
    [Google Scholar]
  29. Kellenberger G., Kellenberger E. 1956; Éude de souches colicinogenes au microscope electronique.. Schweiz. Z. Path. Bakt. 19:582
    [Google Scholar]
  30. Marjai E., Ivánovics G. 1962; A second bacteriocin-like principle of Bacillus megaterium.. Acta microbiol. hung. 9:285
    [Google Scholar]
  31. Nagy E. 1959; Lysogeny and bacteriocinogeny in Bacillus megaterium.. Acta microbiol. hung. 6:337
    [Google Scholar]
  32. Nagy E., Alföldi L., Ivánovics G. 1959; Megacins.. Acta microbiol. hung. 6:327
    [Google Scholar]
  33. Nüske R., Hösel G., Venner H. 1957; Über ein Colicin aus Escherichia coli sg 710.. Biochem. Z. 329:346
    [Google Scholar]
  34. Ozeki H., Stocker B. A. D., De Margerie H. 1959; Production of colicine by single bacteria.. Nature, Lond. 184:337
    [Google Scholar]
  35. Ozeki H., Howarth S., Clowes R. C. 1961; Colicine factors as fertility factors in bacteria.. Nature, Lond. 190:986
    [Google Scholar]
  36. Sneath P. H. A. 1962; Sex factors as episomes.. Brit. med. Bull. 18:41
    [Google Scholar]
/content/journal/micro/10.1099/00221287-35-2-271
Loading
/content/journal/micro/10.1099/00221287-35-2-271
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error