The Intracellular Location of the Agent of Mouse Scrapie Free

Abstract

SUMMARY: Homogenates of brains from mice clinically affected with scrapie have been fractionated by differential centrifugation and equilibration in sucrose density gradients. Most of the infectivity was found in the heavy particulate fraction containing mitochondria and possibly lysosomes.

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1964-02-01
2024-03-28
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