1887

Abstract

SUMMARY: During the formation of incomplete fowl plague virus, normal amounts of viral compounds are synthesized. The S-antigen, however, cannot be demonstrated within the cytoplasm in appreciable amounts by fluorescent antibody. The oligonucleotide pattern and the specific radioactivity of the ribonucleic acid (RNA) of incomplete forms are almost identical with those of standard virus. In contrast to chemically inactivated viruses no indication of multiplicity reactivation was found with incomplete forms. It is suggested that the incomplete forms are lacking in identical pieces of their genome, but contain that part of their RNA which codes for ‘early protein’, S-antigen and haemagglutinin.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-33-2-303
1963-11-01
2022-05-20
Loading full text...

Full text loading...

/deliver/fulltext/micro/33/2/mic-33-2-303.html?itemId=/content/journal/micro/10.1099/00221287-33-2-303&mimeType=html&fmt=ahah

References

  1. Ada G. L., Perry D. T. 1955; Infectivity and nucleic acid content of influenza virus.. Nature, Lond 175:209
    [Google Scholar]
  2. Barry R. D., Waterson A. P., Horne R. W. 1962; Incomplete forms of influenza virus. Z.. Naturf 17b:749
    [Google Scholar]
  3. Breitenfeld P. M., fer W. 1957; The formation of fowl plague virus antigens in infected cells, as studied with fluorescent antibodies.. Virology 4:328
    [Google Scholar]
  4. Davenport F. M., Rott R., fer W. 1960; Physical and biological properties of influenza virus components obtained after ether treatment.. J. exp. Med 112:765
    [Google Scholar]
  5. Dulbecco R., Vogt M. 1954; One-step growth curve of western equine encephalomyelitis virus on chicken embryo cells grown in vitro and analysis of virus yields from single cells.. J. exp. Med 99:183
    [Google Scholar]
  6. Eagle H., Habel K. 1956; The nutritional requirements for the propagation of poliomyelitis virus by the HeLa cell.. J. exp. Med 104:271
    [Google Scholar]
  7. Franklin R. M., Breitenfeld P. M. 1959; The abortive infection of Earle’s L-cells by Fowl Plague virus.. Virology 8:293
    [Google Scholar]
  8. Fulton F., Dumbell K. R. 1949; The serological comparison of strains of influenza virus.. J. gen. Microbiol 3:97
    [Google Scholar]
  9. Hennessen W. 1955; Über eine Influenza-Komplementbindungsreaktion für die Praxis. Z.. Hyg. InfektKr 141:557
    [Google Scholar]
  10. Hirst G. K. 1962; Genetic recombination with Newcastle disease virus, polioviruses, and influenza.. Cold Spr. Harb. Symp. quant. Biol 27:303
    [Google Scholar]
  11. Lief F. S., Henle W. 1956; Studies on the soluble antigen of influenza virus. III. The decreased incorporation of S-antigen into elementary bodies of increasing incompleteness.. Virology 2:782
    [Google Scholar]
  12. Magnus P. von. 1954; Incomplete forms of influenza virus.. Advanc. Virus Res 2:59
    [Google Scholar]
  13. Moffat M. A. I., Holtermann O. A., Hillis W. D. 1960; The development of soluble (S) and viral (v) antigens of influenza A virus in tissue culture as studied by the fluorescent antibody technique. 2. Studies employing a high multiplicity of infection in beef embryo kidney cells.. Acta path, microbiol. scand 50:409
    [Google Scholar]
  14. Morgan C., Rifkind R. A., Rose H. M. 1962; The use of ferritin-conjugated antibodies in electron microscopic studies of influenza and vaccinia viruses.. Cold Spr. Harb. Symp. quant. Biol 27:57
    [Google Scholar]
  15. Rott R., fer W. 1960; Untersuchungen über die hämagglutinierenden nichtinfektiösen Teilchen der Influenza-Viren. I. Die Erzeugung von ‘Inkompletten Formen’ beim Virus der Klassischen Geflügelpest. Z.. Naturf 15b:691
    [Google Scholar]
  16. Rott R., fer W. 1961; Untersuchungen über die hämagglutinierenden nicht-infektiösen Teilchen der Influenza-Viren. II. Vergleichende Untersuchungen über die physikalisch-chemischen und biologischen Eigenschaften der Teilchen. Z.. Naturf 16b:310
    [Google Scholar]
  17. Schäfer W. 1957; Units isolated after splitting fowl plague virus.. In The Nature of Viruses Ed. by Wolstenholm G. E. W., Millar E. C. P. London: Churchill;
    [Google Scholar]
  18. Schäfer W., Rott R. 1962; Herstellung von Virusvakzinen mit Hydroxylamin. Verlauf der Inaktivierung und Wirkung des Hydroxylamins auf verschiedene biologische Eigenschaften einiger Viren. Z.. Hyg. InfektKr 148:256
    [Google Scholar]
  19. Scholtissek C., Rott R. 1961; Zusammenhange zwischen der Synthese von Ribonukleinsaure und Protein bei der Vermehrung eines Virus der Influenza-Gruppe (Virus der klassischen Geflügelpest). Z.. Naturf 16b:663
    [Google Scholar]
  20. Scholtissek C., Rott R. 1963; Synthesis of viral ribonucleic acid by a chemically inactivated influenza virus.. Nature, Lond 199:200
    [Google Scholar]
  21. Scholtissek C., Rott R., fer W. 1962; Verhalten von Viren gegeüber dem Bayer-Präparat A 139. Z.. Naturf 17b:222
    [Google Scholar]
  22. Uhler M., Gard S. 1954; Lipid content of ‘standard’ and ‘incomplete’ influenza virus.. Nature, Lond 173:1041
    [Google Scholar]
  23. Waterson A. P., Rott R., fer W. 1961; The structure of fowl plague virus and virus N. Z.. Naturf 16b:154
    [Google Scholar]
  24. Zimmermann T., fer W. 1960; Effect of p-fluorophenylalanine on fowl plague virus multiplication.. Virology 11:676
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-33-2-303
Loading
/content/journal/micro/10.1099/00221287-33-2-303
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error