%0 Journal Article %A McIntosh, A. F. %A Meyrath, J. %T Size of Inoculum and Nitrogen Metabolism in Aspergillus oryzae %D 1963 %J Microbiology, %V 33 %N 1 %P 57-62 %@ 1465-2080 %R https://doi.org/10.1099/00221287-33-1-57 %I Microbiology Society, %X SUMMARY: The influence of size of inoculum on the nitrogen metabolism of Aspergillus oryzae in submerged culture was studied. In producing a given weight of mycelium a large-inoculum culture, as compared with a small-inoculum culture, showed a higher degree of assimilation of nitrogen and a lower excretion of nitrogen over most of the growth curve. This comparatively greater efficiency of the large-inoculum culture became more pronounced when mechanical stress in the culture was increased. Under high mechanical stress, the inefficiency of a small-inoculum culture was so marked that in forming unit weight of mycelium it utilized more inorganic nitrogen than did a large-inoculum culture. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-33-1-57