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SUMMARY: The non-competitive inhibitors fluoroacetate and arsenite inhibited sporulation and respiration of Venturia inaequalis (Cke.) Wint. to a greater extent than malonate. They also restricted growth. o-Coumaric acid acted similarly to the non-competitive inhibitors but, while not inhibiting growth, it caused changes in the colour of the mycelium, suggesting an altered metabolism. Arsenite increased α-ketoglutarate in the medium and to some extent pyruvate, while o-coumaric acid produced only a slight increase in the concentration of pyruvate. No detectable amounts of succinic acid resulted from the presence of malonate. Injection of o-coumaric acid into scab-infected apple shoots decreased the incidence of disease; malonate had the opposite effect and was strongly phytotoxic.
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