1887

Abstract

SUMMARY:

The apparent non-fixation of tetanus toxin by frog brain emulsion has been re-examined. Frog brain emulsion does fix tetanus toxin, but only with 1/2000th the capacity of mammalian brain emulsion. This low toxinfixing capacity may be connected with the observation that the ganglioside in frog brain, unlike that in mammalian brain, is extractable with aqueous solvents.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-31-3-389
1963-06-01
2021-08-05
Loading full text...

Full text loading...

/deliver/fulltext/micro/31/3/mic-31-3-389.html?itemId=/content/journal/micro/10.1099/00221287-31-3-389&mimeType=html&fmt=ahah

References

  1. Folch J., Arsove S., Meath J. A. 1951; Isolation of brain strandin, a new type of large molecule tissue component. J. biol. Chem. 191:819
    [Google Scholar]
  2. Folch J., Lees M., Sloane Stanley G. H. 1957; A simple method for the isolation and purification of total lipides from animal tissues. J. biol. Chem. 226:497
    [Google Scholar]
  3. Long C., Staples D. A. 1959; Determination of neuraminic acid in crude brain lipids. Biochem. J. 73:385
    [Google Scholar]
  4. Rowson K. E. K. 1961; The action of tetanus toxin in frogs. J. gen. Microbiol. 25:315
    [Google Scholar]
  5. Svennerholm L. 1957; Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method. Biochem. biophys. Acta 24:604
    [Google Scholar]
  6. van Heyningen W. E. 1959a; The fixation of tetanus toxin by nervous tissue. J. gen. Microbiol. 20:291
    [Google Scholar]
  7. van Heyningen W. E. 1959b; Chemical assay of the tetanus toxin receptor in nervous tissue. J. gen. Microbiol. 20:301
    [Google Scholar]
  8. van Heyningen W. E. 1959c; Tentative identification of the tetanus toxin receptor in nervous tissue. J. gen. Microbiol. 20:310
    [Google Scholar]
  9. van Heyningen W. E., Miller P. A. 1961; The fixation of tetanus toxin by ganglioside. J. gen. Microbiol. 24:107
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-31-3-389
Loading
/content/journal/micro/10.1099/00221287-31-3-389
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error