1887

Abstract

SUMMARY: Factor III of anthrax toxin, which increases the lethality of mixtures of factors I and II for mice and decreases their capacity to produce oedema in the skin of rabbits, has been purified. The final preparation showed a single peak in the ultracentrifuge and a single band on paper electro-phoresis. but it might still contain more than one serological component. The final preparation was a protein (N = 15.1%) containing all the usual amino acids but no carbohydrate, phosphorus, lipid or ash.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-29-3-517
1962-11-01
2021-07-30
Loading full text...

Full text loading...

/deliver/fulltext/micro/29/3/mic-29-3-517.html?itemId=/content/journal/micro/10.1099/00221287-29-3-517&mimeType=html&fmt=ahah

References

  1. Harris-Smith P. W., Smith H., Keppie J. 1958; Production in vitro of the toxin of Bacillus anthracis previously recognized in vivo. J. gen. Microbiol. 19 91
    [Google Scholar]
  2. Sargeant K., Stanley J. L., Smith H. 1960; The serological relationship between purified preparations of factors I and II of the anthrax toxin produced in vivo and in vitro. J. gen. Microbiol. 22 219
    [Google Scholar]
  3. Smith H., Keppie J., Stanley J. L. 1955; The chemical basis of the virulence of Bacillus anthracis. V. The specific toxin produced by B. anthracis in vivo. Brit. J. exp. Path. 36 460
    [Google Scholar]
  4. Smith H., Tempest D. W., Stanley J. L., Harris-Smith P. W., Gallop R. C. 1956; The chemical basis of the virulence of Bacillus anthracis. VII. Two components of the anthrax toxin; their relationship to known immunizing aggressins. Brit. J. exp. Path. 37 263
    [Google Scholar]
  5. Stanley J. L., Sargeant K., Smith H. 1960; Purification of factors I and II of the anthrax toxin produced in vivo. J. gen. Microbiol. 22 206
    [Google Scholar]
  6. Stanley J. L., Smith H. 1961; Purification of factor I and recognition of a third factor of the anthrax toxin. J. gen. Microbiol. 26 49
    [Google Scholar]
  7. Thorne C. B., Molnar D. M., Strange R. E. 1960; Production of toxin in vitro by Bacillus anthracis and its separation into two components. J. Bad. 79 250
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-29-3-517
Loading
/content/journal/micro/10.1099/00221287-29-3-517
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error