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Volume 28, Issue 3

Bacterial Spore Antigens: a Review Free

Abstract

SUMMARY: Agglutinogens and precipitinogens have been detected in the spores of many species of aerobic and anaerobic spore-formers and these antigens are distinct from those of the vegetative growth phases of the corresponding organisms. Spore antigens are heat resistant and antibody response is elicited by the injection of autoclaved spores into rabbits. Injection of living spores leads to the development of antibodies reacting with vegetative cell antigens in addition to spore antibodies.

Agglutinogens tend to show subspecies distribution in some aerobic species but spore precipitinogens appear to be mainly species specific in aerobes. Less information is available about anaerobes where a similar pattern of specificity is suggested. Data about the antigenic structure of the spore and the antigenic changes accompanying sporulation and germination are scant; it is in these aspects of the subject that the most significant progress is to be anticipated.

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© Society for General Microbiology 1962
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1962-07-01
2024-04-25
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References

  1. Bekker J. H. 1944; The antigenic properties of bacterial spores. Leeuwenhoek ned. Tijdschr. 10:67
     [Google Scholar]
  2. Cherry W. B., Freeman E. M. 1959; Staining bacterial smears with fluorescent antibody. V. The rapid identification of Bacillus anthracis in culture and in human and murine tissues. Zbl. Bakt. I Abt. Orig. 175:582
     [Google Scholar]
  3. Chimera G. 1916; Antibodies of spores. Clin. vet. Rass. Pol. Sanit. e. Ig. 39:479 (Chem. Abstr. (1917), 11, 2930.)
    [Google Scholar]
  4. Chu H. P. 1951; Quoted by McCloy, E. W. (1951). Studies on a lysogenic Bacillus strain. I. A bacteriophage specific for Bacillus anthracis. J. Hyg., Camb. 49:114
     [Google Scholar]
  5. Conn H. J. 1930; The identity of Bacillus subtilis. J. infect. Dis. 46:341
     [Google Scholar]
  6. Davies S. N. 1951; The serology of Bacillus polymyxa. J. gen. Microbiol. 5:807
     [Google Scholar]
  7. DeFalle W. 1902; Recherches sur les anticorps des spores. Ann. Inst. Pasteur 16:756
     [Google Scholar]
  8. Delpy P. L., Chamsy H. M. 1949; Sur la stabilisation des suspensions sporulée de B. anthracis par l’action de certains antiseptiques. C.R. Acad. Sci., Paris 228:1071
     [Google Scholar]
  9. Doak B. W., Lamanna C. 1948; On the antigenic structure of the bacterial spore. J. Bact. 55:373
     [Google Scholar]
  10. Dowdle W. R., Hansen P. A. 1961; A phage-fluorescent antiphage staining system for Bacillus anthracis. J. infect. Dis. 108:125
     [Google Scholar]
  11. Ferry N. S., Fisher L. W. 1924; Studies of the immunising properties of bacterial antigens prepared after various methods. Brit. J. exp. Path. 5:185
     [Google Scholar]
  12. Fowler E. H., Harrison J. A. 1953; Microscopic examination of spores of S. subtilis in agglutinative reactions. Bact. Proc.28
     [Google Scholar]
  13. Gibson T. 1937; The identity of Bacillus subtilis and its differentiation from other spore-forming bacteria. Proc. Soc. agric. Bact. (abstr.)
    [Google Scholar]
  14. Gibson T. 1944; A study of Bacillus subtilis and related organisms. J. Dairy Res. 13:248
     [Google Scholar]
  15. Halvorson H. O. 1957; Spores. Amer. Inst. Biol. Sci. Publ.5
     [Google Scholar]
  16. Howie J. W., Cruickshank J. 1940; Bacterial spores as antigens. J. Path. Bact. 50:235
     [Google Scholar]
  17. Jacobs S. E., Clegg L. F. L. 1957; Symposium on the formation and germination of bacterial spores. J. appl. Bact. 20305
     [Google Scholar]
  18. Knaysi G. 1948; The endospore of bacteria. Bact. Rev. 12:19
     [Google Scholar]
  19. Knight B. C. J., G. & Proom H. 1950; A comparative survey of nutrition and physiology of mesophilic species in the genus Bacillus. J. gen. Microbiol. 4:508
     [Google Scholar]
  20. Krauskopf E. J., McCoy E. 1937; The serology of spores of Bacillus niger with special reference to the H antigen. J. infect. Dis. 61:251
     [Google Scholar]
  21. Lamanna C. 1940a; The taxonomy of the genus Bacillus. II. Differentiation of small celled species by means of spore antigens. J. infect. Dis. 67:193
     [Google Scholar]
  22. Lamanna C. 1940b; The taxonomy of the genus Bacillus. III. Differentiation of the large celled species by means of spore antigens. J. infect. Dis. 67:205
     [Google Scholar]
  23. Lamanna C. 1942; The status of Bacillus subtilis, including a note on the separation of precipitinogens from bacterial spores. J. Bact. 44:611
     [Google Scholar]
  24. Lamanna C., Eisler D. 1960; Comparative study of the agglutinogens of the endospores of Bacillus anthracis and Bacillus cereus. J. Bad. 79:435
     [Google Scholar]
  25. Lamanna C., Jones L. 1961; Antigenic relationship of the endospores of Bacillus cereus like insect pathogens to Bacillus cereus and Bacillus anthracis. J. Bact. 81:622
     [Google Scholar]
  26. LeCorroller Y. 1958; A propos de la transformation de souches banales de Bacillus cereus Frank, et Frank, en souches cristallophores pathogenes pour les insectes. Ann. Inst. Pasteur 94:670
     [Google Scholar]
  27. Mandia J. W. 1955; The position of Clostridium tetani within the serological schema for the proteolytic clostridia. J. infect. Dis. 97:66
     [Google Scholar]
  28. Meisel H., Albrycht H., Rymkiewicz D. 1959; Kappa toxin in extracts from mechanically disrupted cells and spores of Clostridium perfringens Type A. Bull. Acad, pol. Sci. 7:259
     [Google Scholar]
  29. Meisel H., Rymkiewicz D. 1957; Antigenic properties of Clostridium tetani spores devoid of serologically active components of vegetative cells by treatment with alkali or enzymes. Med. dosw. Mikrobiol. 9:375 (in Polish. English Summary)
    [Google Scholar]
  30. Meisel H., Rymkiewicz D. 1958a; Presence of cellular antigens O and H in endospores of proteolytic Clostridia. Bull. Acad. pol. Sci. 6:99
     [Google Scholar]
  31. Meisel H., Rymkiewicz D. 1958b; Über die serologischen Eigenschaften der durch Enzymbehandlung frei-präparierten Bakteriesporen. Schweiz. Z. Path. 21:866
     [Google Scholar]
  32. Meisel H., Rymkiewicz D. 1959; Spore antigens in the classification of proteolytic Clostridia. Med. dosw. Mikrobiol. 11:1 (In Polish. English Summary.)
    [Google Scholar]
  33. Mellon R. R., Anderson L. M. 1919; Immunological disparities of spore and vegetative stages of Bacillus subtilis. J. Immunol. 4:203
     [Google Scholar]
  34. Moussa R. S. 1956; Antigenic formulae for Clostridium septicum and Clostridium chauvoei. Ph.D. Thesis, University of Leeds
    [Google Scholar]
  35. Moussa R. S. 1959; Antigenic formulae for Clostridium septicum and Clostridium chauvoei. J. Path. Bact. 77:341
     [Google Scholar]
  36. Noble A. 1919; A method for the production of a homogeneous suspension of Bacillus anthracis to be used in agglutination reactions. J. Immunol. 4:105
     [Google Scholar]
  37. Noble A. 1927; A rapid method for the macroscopic agglutination test. J. Bact. 14:287
     [Google Scholar]
  38. Norris J. R. 1957; A bacteriolytic principle associated with cultures of Bacillus cereus. J. gen. Microbiol. 16:1
     [Google Scholar]
  39. Norris J. R., Watson D. H. 1960; An electron microscope study of sporulation and protein crystal formation in Bacillus cereus var. alesti. J. gen. Microbiol. 22:744
     [Google Scholar]
  40. Norris J. R., Wolf J. 1961; A study of antigens of the aerobic spore-forming bacteria. J. appl. Bact. 24:42
     [Google Scholar]
  41. Proom H., Knight B. C. J. G. 1955; The minimal nutritional requirements of some species in the genus Bacillus. J. gen. Microbiol. 13:474
     [Google Scholar]
  42. Schlossberger H. 1951; Über das Verhalten der Chromatinsubstanz und die antigenen Eigenschaften der Sporen von Bacillus sphaericus. Schweiz. Z. Path. 14:509
     [Google Scholar]
  43. Schweinsberg H. 1951; Serologische Untersuchungen an einem Sporenbildner (Bacillus sphaericus) zur Feststellung der Antigenstruktur der Endospore. Z. Immun.-Forsch. 109:27
     [Google Scholar]
  44. Shattock P. M. F. 1955; The use of serology in the classification of micro-organisms. J. gen. Microbiol. 12:367
     [Google Scholar]
  45. Smith N. R., Gordon R. E., Clark F. E. 1952; Aerobic sporeforming bacteria. Monogr. U.S. Dep. Agric. 16:
     [Google Scholar]
  46. Starin W. A., Dack G. 1923; Agglutination studies of Clostridium botulinum. J. infect. Dis. 33:169
     [Google Scholar]
  47. Sussman M. 1959; The relationship between Clostridium histolyticum and Clostridium sporogenes.. Ph.D. Thesis, University of Leeds
    [Google Scholar]
  48. Teale F. H., Bach E. 1919; Studies in bacterial infection. III. The fate of washed spores on inoculation into animals, with special reference to the nature of bacterial toxaemia. J. Path. Bact. 23:315
     [Google Scholar]
  49. Tomcsik J. 1956; Antibodies as indicators for bacterial surface structures. Annu. Rev. Microbiol. 10:213
     [Google Scholar]
  50. Tomcsik J., Baumann-Grace J. B. 1959; Specific exosporium reaction of Bacillus megaterium. J. gen. Microbiol. 21:666
     [Google Scholar]
  51. Toumanoff C. 1956; Virulence expérimentale d’une souche banale de Bacillus cereus Frank, et Frank, pour les cheniles de Galleria melonella L. et Pieris brassicae. Ann. Inst. Pasteur 90:660
     [Google Scholar]
  52. Vennes J. W., Gerhardt P. 1957; Further serological analysis of isolated cellular structures of Bacillus megaterium. Bact. Proc.105
     [Google Scholar]
  53. Vennes J. W., Gerhardt P. 1959; Antigenic analysis of cell structures isolated from Bacillus megaterium. J. Bact. 77:581
     [Google Scholar]
  54. Walker P. D. 1959; A study of biochemical, physiological and serological properties of some strains of Bacillus stearothermophilus. Ph.D. Thesis, University of Leeds
    [Google Scholar]
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