%0 Journal Article %A Chapman, P. J. %A Dagley, S. %T Oxidation of Homogentisic Acid by Cell-free Extracts of a Vibrio %D 1962 %J Microbiology, %V 28 %N 2 %P 251-256 %@ 1465-2080 %R https://doi.org/10.1099/00221287-28-2-251 %I Microbiology Society, %X SUMMARY: Acetoacetic acid is a product of degradation of homogentisic acid by cell-free extracts of a vibrio grown with phenylacetic acid as sole carbon source. 4-Maleylacetoacetate was identified as a reaction intermediate; reduced glutathione was a cofactor for this enzymic degradation. These reactions are similar to those catalysed by enzymes of rat liver. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-28-2-251