SUMMARY: A soluble trypanosomal antigen occurs in the serum of rats infected with This ‘exoantigen’ is probably not a protein and is electrophoretically a slow-moving component in the serum. The exoantigen which is also present on the surface as an agglutinogen appears to protect the trypanosomes against adverse environment, preserving their infectivity for long periods Rats and mice immunized with exoantigen are protected against infection with the homologous strain of Rabbits infected chronically with form antibodies to exoantigen. On disintegration of the trypanosomes, in addition to exoantigen, ‘bound’ antigens are released. In the natural disease exoantigens induce antibodies which may be concerned with protection against further infection.


Article metrics loading...

Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error