SUMMARY: Carbon dioxide stimulates the growth of and the production of the extracellular enzyme dextransucrase. The growth of cultures in the presence of CO resulted in the incorporation of carbon-14 into aspartic acid, with lesser amounts in threonine, glutamic acid, adenine, guanine, uridylic acid and cytidylic acid. Organisms grown with labelled aspartic acid did not utilize it to any extent; the principal source of this amino acid was from CO-fixation reactions. The stimulation of growth by CO is considered to be due to biosynthetic reactions involving CO which lead to a sufficient supply of the intermediates required in nucleic acid and protein synthesis.


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