%0 Journal Article %A Ryan, F. J. %A Kiritani, K. %T Effect of Temperature on Natural Mutation in Escherichia coli %D 1959 %J Microbiology, %V 20 %N 3 %P 644-653 %@ 1465-2080 %R https://doi.org/10.1099/00221287-20-3-644 %I Microbiology Society, %X SUMMARY: The mutation rate from histidine auxotrophy to prototrophy in Escherichia coli was measured during growth and in the stationary phase at different temperatures. Dining growth the rate of mutation/mutable unit/hr. had the same temperature coefficient as the rate of growth. Therefore the rate of mutation/ mutable unit/generation was the same at all temperatures. The temperature coefficient of the rate of mutation/unit/hr. during the stationary phase may be the same as that during growth, indicating that although mutation is slower in this phase it may involve the same process as during growth. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-20-3-644