SUMMARY: Staphylococcal strains which showed a range of reactions with the phages 47C, 52, 52A, 80 and 81 were examined for changes in phage sensitivity following artificial lysogenization. The lysogenic phages used were isolated from strains of three different phage-typing patterns and differed in serology. The changes in phage reactions thus produced included: (1) immunity to the B phages, 52, 52A and 80 produced by a B phage; (2) immunity to the A phage 81 produced by a serologically unrelated F phage; (3) immunity to phage 47C and sensitivity to phages 52 and 52A produced by a number of A phages. The mechanisms whereby a variety of typing patterns may be obtained within a related group of staphylococci are discussed.


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