1887

Abstract

SUMMARY: The growth characteristics of eight strains of were studied in defined liquid media. Two of these strains (1017, 1018), which are both very virulent on intracerebral injection into mice, were found to have growth idiosyncrasies. Both these strains differed from typical virulent pertussis strains and from a degraded strain in that they needed more magnesium and a different gas phase (carbon dioxide and oxygen) for optimal growth in defined liquid medium. Both strains were inhibited by crystalline lysozyme (100 mg./ml.) in defined medium, whereas typical virulent strains and a degraded strain were insensitive to it.

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/content/journal/micro/10.1099/00221287-20-3-532
1959-06-01
2024-04-19
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References

  1. Ainsworth G. C., Brown A. M., Brownlee G. 1947; Aerosporin, an antibiotic produced by Bacillus aerosporin, Greer. Nature; Lond: 160263
    [Google Scholar]
  2. Andersen E. K. 1952; Serological studies on H. pertussis, H. para pertussis and H. bronchisepticus; preliminary report. Acta path, microbiol. scand 30:54
    [Google Scholar]
  3. Brown A. M. 1958; Intracerebral infection of mice with Haemophilus pertussis and passive protection by hyperimmune rabbit sera. J. gen. Microbiol 18:48
    [Google Scholar]
  4. Cohen S. M., Wheeler M. W. 1946; Pertussis vaccines produced with phase I cultures grown on fluid medium. Amer. J. publ. Hlth 36:371
    [Google Scholar]
  5. Jebb W. H., Tomlinson A. H. 1955; The nutritional requirements of Haemophilus pertussis . J. gen. Microbiol 13:1
    [Google Scholar]
  6. Kendrick P. L., Eldering G., Dixon M. K., Misner J. 1947; Mouse protection tests in the study of pertussis vaccine. A comparative series using the intracerebral route for challenge. Amer. J. publ. Hlth 37:803
    [Google Scholar]
  7. Lacey B. W. 1951; Antigenic modulation of Haemophilus pertussis . J. gen. Microbiol 5:xxi
    [Google Scholar]
  8. Mazloum H. A., Rowley D. 1955; The growth requirements of Haemophilus pertussis on solid media. J. Path. Bact 70:439
    [Google Scholar]
  9. Miles A. A., Misra S. S. 1938; The estimation of the bactericidal power of blood. J. Hyg., Camb 38:732
    [Google Scholar]
  10. Rowatt E. 1957; The growth of Bordetella pertussis: a review. J. gen. Microbiol 17:297
    [Google Scholar]
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