The Formation of Methionine by a Methionine-Requiring Mutant of Neurospora crassa

SUMMARY: A methionine-requiring mutant of Neurospora crassa incorporated 35SO4 into methionine. This incorporation represents net synthesis of methionine by the mutant. It is quite likely that methionine synthesis proceeds by the normal pathway in the mutant. Not all of the normal proteins can be synthesized when methionine supplies are limiting, accounting for the inability of the mutant to begin growth without a long lag even though methionine can be synthesized.