1887

Abstract

SUMMARY: A methionine-requiring mutant of incorporated SO into methionine. This incorporation represents net synthesis of methionine by the mutant. It is quite likely that methionine synthesis proceeds by the normal pathway in the mutant. Not all of the normal proteins can be synthesized when methionine supplies are limiting, accounting for the inability of the mutant to begin growth without a long lag even though methionine can be synthesized.

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/content/journal/micro/10.1099/00221287-20-2-237
1959-04-01
2024-12-14
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References

  1. Beadle G. W., Tatum E. L. 1945; Neurospora. II. Methods of producing and detecting mutations concerned with nutritional requirements. Amer. J. Bot 32:678
    [Google Scholar]
  2. Block R. J., Durrum E. L., Zweig G. 1955 A Manual of Paper Chromatography and Paper Electrophoresis484 pp. New York: Academic Press, Inc;
    [Google Scholar]
  3. Bonner D. M. 1951; Gene-enzyme relationships in Neurospora. Cold. Spr. Harb. Symp. quant. Biol 16:143
    [Google Scholar]
  4. Bonner D. M., Yanofsky C., Partridge C. W. H. 1952; Incomplete genetic blocks in biochemical mutants of Neurospora. Proc. nat. Acad. Sci., Wash 38:25
    [Google Scholar]
  5. Cohn W. E., Volkin E. 1957; The nucleic acids. Ann. Rev. Biochem 26:491
    [Google Scholar]
  6. Horowitz N. H. 1950; Biochemical genetics of Neurospora. Advanc. Gentet 3:33
    [Google Scholar]
  7. Minagawa T., Wagner B., Strauss B. 1959; The nucleic acid content of Neurospora crassa . Arch. Biochem. Biophys in the Press
    [Google Scholar]
  8. Roberts R. B., Abelson P. H., Cowie D. B., Bolton E. T., Britten R. J. 1955; Studies of biosynthesis in Escherichia coli . Publ. Carneg. Instn607
    [Google Scholar]
  9. Strauss B. S., Vaharu T., Frickey P. 1956; Studies on the lethal effect of incorporated P32 and S35 in Neurospora crassa . Rad. Res 5:25
    [Google Scholar]
  10. Strauss B. S. 1958a; Cell death and ‘unbalanced growth’ in Neurospora. J. gen. Microbiol 18:658
    [Google Scholar]
  11. Strauss B. S. 1958b; Effect of the distribution of incorporated sulfur on the lethal effect of incorporated 35SO4 . Proc. 10th Int. Congr. Genet in the Press
    [Google Scholar]
  12. Woodward Y. W., DeZeeuw J. R., Srb A. M. 1954; The separation and isolation of particular biochemical mutants of Neurospora by differential germination of conidia followed by filtration and selective plating. Proc. nat. Acad. Sci., Wash 40:192
    [Google Scholar]
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