1887

Abstract

Summary: A new gene, is described in This gene is shown to be a modifier of the nutritional response of strains containing the gene, and is not nutritionally detectable in the absence of the mutant locus. The gene is additionally characterized by a decreased ability to synthesize thiamine from thiazole and pyrimidine; appears to modify only strains because of their unusually high thiamine requirements. The nutritional responses of strains containing either or loci are not affected by the presence of Both and are anomalous in the condensation of pyrimidine and thiazole. The probability that may be an isoallele of is based upon a similarity of metabolic pattern and upon location on chromosome III. The failure to obtain recombination in crosses between strains containing and constitutes additional support for their allelism.

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/content/journal/micro/10.1099/00221287-20-1-43
1959-02-01
2024-04-24
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