SUMMARY: Glutamine is not required for staphylococcal growth, and was found to be synthesized by staphylococci from NH and glutamic acid in the presence of glucose. The amount of glutamine found was, however, much less than that of the NH reacting. Similar relationships were found in and was, however, outstanding in possessing a powerful glutaminase which could easily be separated from the cells; in this it differed markedly from Glutaminase activity was also demonstrated in yeasts, where its occurrence has been previously a matter of dispute.

Glutamine is essential for growth of certain β-haemolytic streptococci; it accelerates their main energy-yielding reaction, glycolysis, and it is hydrolysed to glutamic acid and NH during this process (McIlwain, 1946 , ) Certain of these associations may be explained by the need of energy for the assimilation of glutamic acid and glutamine (Gale, 1947). This requirement (Taylor, 1947), like that for glutamine in growth (McIlwain, Fildes, Gladstone & Knight, 1939), is different in different microbial species. We have now studied the association between glucose, glutamine, glutamic acid and ammonia in several micro-organisms.


Article metrics loading...

Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error