1887

Abstract

Summary: Fifty-six toxigenic mitis and mitis-like strains isolated in the western part of the United States and Canada were examined for lysogeny and for the relationship of their phages to conversion to toxigenicity. Twenty-five strains (46 %) were demonstrably lysogenic. Twenty-two of the phages from the toxigenic strains were able to convert a sensitive non-toxigenic strain to toxigenicity. Due to technical limitations three phages could not be tested in a similar manner. On the basis of serological relationships, cross-immunizing ability and host range all 22 converting phages proved to be very closely related. They were also related to - and -phages previously studied in connexion with the phenomenon of conversion to toxigenicity by bacteriophage.

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/content/journal/micro/10.1099/00221287-19-3-634
1958-12-01
2024-10-03
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References

  1. Christensen W.B. 1946; Urea decomposition as a means of differentiating Proteus and Paracolon cultures from each other and from Salmonella and Shigella types. J. Bact 52:461
    [Google Scholar]
  2. Christensen P.E. 1957; Studies on lysogenicity in C. diphtheriae. Acta path.microbwl. scand 41:67
    [Google Scholar]
  3. Diagnostic Procedures and Reagents 1950, Third edition.. American Public Health Association Inc., New York, N.Y.
  4. Freeman V.J. 1951; Studies on the virulence of bacteriophage-infected strains of Corynebacterium diphtheriae. J. Bact 61:675
    [Google Scholar]
  5. Groman N.B., Eaton M. 1955; Genetic factors in Corynebacterium diphtheriae conversion. J. Bact 70:637
    [Google Scholar]
  6. Hewitt L.F. 1952; Diphtheria bacteriophages and their relation to the development of bacterial variants. J. gen.Microbiol 7:362
    [Google Scholar]
  7. Hewitt L.F. 1954; Mechanism of virulence transfer by bacterial viruses. J. gen.Microbiol 11:272
    [Google Scholar]
  8. Keogh E.V., Simmons R.T., Anderson G. 1938; Type specific bacteriophages for Corynebacterium diphtheriae. J. Path. Bact 46:565
    [Google Scholar]
  9. Minzel G.H., Freeman V.J. 1950; Serologic studies of Corynebacterium diphtheriae. 1.The use of a surface active agent in the preparation of uniform suspensions of C. diphtheriae for serologic typing. Amer. J. publ. Hlth 51:300
    [Google Scholar]
  10. Mueller J.H., Miller P.A. 1946; A new tellurite plating medium and some comments on the laboratory diagnosis of diphtheria. J. Bact 51:743
    [Google Scholar]
  11. Narbutowicz B. 1955; Studies on the conversion to toxigenicity of phage- infected atoxic strains of Corynebacterium diphtheriae. Acta microbid.polonica, 4:245
    [Google Scholar]
  12. Parsons E.I. 1955; Induction of toxigenicity in non-toxigenic strains of C. diphtheriae with bacteriophages derived from non-toxigenic strains. Proc. Soc. exp. Biol., N.Y 90:91
    [Google Scholar]
  13. Thibaut J., Frédéricq P. 1952; Liberation de bactériophage par des souches lysogènes de C. diphtheriae sous l’effet des rayons ultraviolets. C.P. Soc. Biol., Paris 146:1627
    [Google Scholar]
  14. Thibaut J., Frédéricq P. 1956; Recherches sur la classification des souches de Corynebacterium diphtheriae type gravis d’après leur sensibilité à divers bactériophages. C.R. Soc. Biol., Paris 150:1039
    [Google Scholar]
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