RT Journal Article SR Electronic(1) A1 Van Dijck, P. J. A1 De Somer, P.YR 1958 T1 Ramycin: A New Antibiotic JF Microbiology, VO 18 IS 2 SP 377 OP 381 DO https://doi.org/10.1099/00221287-18-2-377 PB Microbiology Society, SN 1465-2080, AB SUMMARY: A strain of Mucor ramannianus from Campine forest soil was found to secrete an antibiotic, for which the name Ramycin is proposed. It is especially active against Gram-positive micro-organisms and Myobacterium tuberculosis H37Rv, but sensitive organisms quickly acquire resistance to it. Although it is not very toxic, it possesses a necrotic action on tissues. Ramycin can protect mice against streptococcal and staphylococcal infections but not against H37Rv. Ramycin crystallizes in orthorhombic plates. The new antibiotic is an optically-inactive unsaturated hydroxy acid, containing C, H and O only., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-18-2-377