1887

Abstract

SUMMARY: A strain of from Campine forest soil was found to secrete an antibiotic, for which the name Ramycin is proposed. It is especially active against Gram-positive micro-organisms and H37Rv, but sensitive organisms quickly acquire resistance to it. Although it is not very toxic, it possesses a necrotic action on tissues. Ramycin can protect mice against streptococcal and staphylococcal infections but not against H37Rv. Ramycin crystallizes in orthorhombic plates. The new antibiotic is an opticallyinactive unsaturated hydroxy acid, containing C, H and O only.

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/content/journal/micro/10.1099/00221287-18-2-377
1958-04-01
2019-12-13
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-18-2-377
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