@article{mbs:/content/journal/micro/10.1099/00221287-18-1-58, author = "Kaplan, C.", title = "The Heat Inactivation of Vaccinia Virus", journal= "Microbiology", year = "1958", volume = "18", number = "1", pages = "58-63", doi = "https://doi.org/10.1099/00221287-18-1-58", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-18-1-58", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "SUMMARY: Heat inactivation curves of vaccinia virus between 50° and 60° indicate that the virus is heterogeneous in its heat sensitivity. The proportion of heat-resistant particles varies inversely with the temperature of exposure. The inactivation of heat-sensitive virus is temperature dependent and seems to be a first-order reaction, while the heat-resistant fraction is inactivated at a constant slow rate unrelated to temperature over the range 50°-60°.", }