SUMMARY: The effect of the ionic composition of the medium on the respiration of resting-cell suspensions of two Gram-negative micro-organisms has been investigated. Potassium or rubidium salts with Cl, Br or I as anion were found to be necessary for the maximal rates of oxidation of glutamate or glucose by , and KCl or KSO by . The pH value of the medium and the concentration of the substrate influenced the effect of the electrolytes. Under certain conditions, a synergistic effect of Na ion was observed. The same ion mixtures which supported the respiration caused the maximal swelling of the bacterial cells.


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