RT Journal Article SR Electronic(1) A1 Ball, S. A1 Bessell, Christine J. A1 Mortimer, AileenYR 1957 T1 The Production of Polyenic Antibiotics by Soil Streptomycetes JF Microbiology, VO 17 IS 1 SP 96 OP 103 DO https://doi.org/10.1099/00221287-17-1-96 PB Microbiology Society, SN 1465-2080, AB SUMMARY: Sixty Streptomyces isolates which produce polyene antibiotics were isolated from 25 soil samples collected in different parts of the world. Of these isolates 25 produced tetraenes, 23 produced pentaenes, 1 produced a hexaene, and 15 produced heptaenes. One isolate produced simultaneously a tetraene and a pentaene, another produced a tetraene and a heptaene, and a third produced a tetraene, a pentaene and a heptaene. The antibiotics showed activity against a wide range of fungi; the minimum inhibitory concentrations against Saccharomyces ceremsiae, Aspergillus niger, Mucor racemosus, Candida albicans, Fusarium culmorum and Trichophyton mentagrophytes are given for 10 of them. The distribution of activity between culture filtrate and mycelium is given for 14 of the antibiotics., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-17-1-96