1887

Abstract

SUMMARY:Gram-negative bacilli were obtained from the Oxford strain of in the presence of benzylpenicillin, and single organisms were isolated from these bacilli. The properties of bacilli derived from the isolates were compared with those of the parent staphylococci. The two types of organism differed strikingly in morphology, staining and various biochemical reactions. The bacilli were much more resistant to benzylpenicillin than the parent staphylococcus, but much less resistant to polymyxin. Staphylococci were recovered from all the strains of bacilli. More than half of the recovered strains resembled the original staphylococcus in all properties tested, including phage type, when first isolated. The remainder formed a somewhat heterogeneous group, differing in some properties from the parent. Later, some members of this heterogeneous group also became indistinguishable from the original staphylococcus.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-16-3-614
1957-06-01
2022-01-16
Loading full text...

Full text loading...

/deliver/fulltext/micro/16/3/mic-16-3-614.html?itemId=/content/journal/micro/10.1099/00221287-16-3-614&mimeType=html&fmt=ahah

References

  1. Anderson E.S., Williams R.E.O. 1956; Bacteriophage typing of enteric pathogens and staphylococci and its use in epidemiology: a review.. J. clin. Path. 9:94
    [Google Scholar]
  2. Barer R., Saunders-Singer A.E. 1951; A low-power micromanipulator and microdissector.. J. sci. Instrum. 28:65
    [Google Scholar]
  3. Bellamy W.D., Klimek J.W. 1948; Some properties of penicillin-resistant staphylococci.. J. Bact. 55:153
    [Google Scholar]
  4. Boivin A., Tulasne R., Vendrely R., Minck R. 1947 Arch. Sci. Physiol. 1:307
    [Google Scholar]
  5. Cooper P.D. 1956; Site of action of radiopenicillin.. Bact. Rev. 20:28
    [Google Scholar]
  6. Crawford K., Abraham E.P. 1957; The synergistic action of cephalosporin C and benzylpenicillin against a penicillinase-producing strain of Staphylococcus aureus.. J. gen. Microbiol. 16:604
    [Google Scholar]
  7. De Fonbrune P. 1949 Technique de micromanipulation. Paris: Masson et Cie;
    [Google Scholar]
  8. Florey H.W., Chain E., Heatley N.G., Jennings M.A., Sanders A.G., Abraham E.P., Florey M.E. 1949 Antibiotics chapter 35. Oxford Medical Publications;
    [Google Scholar]
  9. Freeman V.J. 1951; Studies on the virulence of bacteriophage-infected strains of Corynebaderium diphtheriae.. J. Bact. 61:675
    [Google Scholar]
  10. Gale E.F., Rodwell A.W. 1948; Amino acid metabolism of penicillin-resistant staphylococci.. J. Bact. 55:161
    [Google Scholar]
  11. Gale E.F., Rodwell A.W. 1949; The nature of resistance to penicillin in Staphylococcus aureus.. J. gen. Microbiol. 3:127
    [Google Scholar]
  12. Gardner A.D. 1940; Morphological effects of penicillin on bacteria.. Nature; London: 146837
    [Google Scholar]
  13. Hewitt L.F. 1954; The effect of certain antibiotics and other chemotherapeutic agents on lysogenicity and virulence transfer by bacterial viruses in Coryne-baderium diphtheriae.. J. gen. Microbiol. 11:288
    [Google Scholar]
  14. Kawamata J., Shigeto T. 1956; Altered growth requirements accompanying penicillin resistance.. Bull. Hyg. 31:439
    [Google Scholar]
  15. Klimek J.W., Cavallito C.J., Bailey J.H. 1948; Induced resistance of Staphylococcus aureus to various antibiotics.. J. Bact. 55:139
    [Google Scholar]
  16. Lederberg J. 1956; Bacterial protoplasts induced by penicillin.. Proc. nat. Acad. Sci., Wash. 42:574
    [Google Scholar]
  17. Mitchell P. 1957; Penicillin and the logic of chemotherapy. First European Symposium on Antibiotics, Milan.. G. Microb. (in the Press)
    [Google Scholar]
  18. Newton B.A. 1956; The properties and mode of action of the polymyxins.. Bact. Rev. 20:14
    [Google Scholar]
  19. Rake G., Mckee C.M., Hamke D.M., Houck C.L. 1944; Studies on penicillin. II. Observations on therapeutic activity and toxicity.. J. Immunol. 48:271
    [Google Scholar]
  20. Szybalski W. 1955; ‘Lamarckian’ inheritance of streptomycin resistance.. Antibiot. Ann. 1954–55
    [Google Scholar]
  21. Voureka A. 1952; Induced variations in a penicillin-resistant staphylococcus.. J. gen. Microbiol. 6:352
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-16-3-614
Loading
/content/journal/micro/10.1099/00221287-16-3-614
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error