The Action of Phenol and 2-Phenoxyethanol on the Oxidation of Various Substances by Escherichia coli and by a Disrupted Cell Preparation of the Orǵanism
SUMMARY: The effects of phenol and 2-phenoxyethanol on the oxygen uptake of washed suspensions and a disrupted cell preparation of Escherichia coli, with different substrates, has been further investigated. Stimulation of oxygen uptake with mannitol or glucose as substrate was not due to an increase in the viable population or associated with an uncoupling effect. The results obtained with a disrupted cell preparation capable of oxidizing glucose and lactic acid to pyruvic acid, on comparison with results with intact organisms, suggest that enzyme location may account for the differences in inhibitory activity obtained with different substrates.
DyarM.T.,
OrdalE.J.1946; Elektrokinetic studies on bacterial surfaces.I. The effects of surface-active agents on the electrophoretic mobilities of bacteria. J. Bact. 51:149
GaleE.F.,
TaylorE.S.1947; The action of tyrocidin and some detergent substances in releasing the amino-acids from the internal environment of Strep, Faecalis.
. J. Gen. Microbiol. 1:77
HugoW.B.,
StreetH.E.1952; The effect of phenol 2-phenoxyethanol and cetyltrimethylammonium bromide on the oxidation of various substrates by Escherichia Coli.
. J. Gen. Microbiol. 6:90
McQuillenK.1950; The bacterial surface. I. The effect of cetyltrimethylammonium bromide on the electrophoretic mobility of certain Gram-positive bacteria. Biochim. Biophys. Acta 5:463
SaltonM.R.J.1951; The adsorption of cetyltrimethylammonium bromide by bacteria, its action in releasing cellular constituents and its bactericidal effects. J. gen. Microbiol. 5:391
The Action of Phenol and 2-Phenoxyethanol on the Oxidation of Various Substances by Escherichia coli and by a Disrupted Cell Preparation of the Orǵanism