1887

Abstract

is a primary colonizer of dental plaque and a major player in subacute bacterial endocarditis. In the present study, the authors report that an ORF (ORF3) located 77 bp downstream of the operon on the FW213 chromosome complements an thiol peroxidase () mutation in glutamine synthetase (GS) protection assays and that GS is protected by the ORF3 gene product in cell extracts. In addition, the putative streptococcal peroxidase (Tpx) protects from stress caused by HO and is induced by oxygen, as revealed by Northern blot analysis. Taken collectively, these findings support a thiol-dependent antioxidant activity for Tpx in .

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2002-03-01
2020-01-20
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