1887

Abstract

Four potential binding sites for LexA were identified upstream of the gene. A mutational analysis of these sites in a reporter construct revealed that only one of these SOS boxes was required for DNA-damage-mediated regulation of expression. A novel DNA-damage-inducible gene, , was identified that was divergently transcribed relative to ; the other three SOS boxes were found to be involved in regulating expression of this novel mycobacterial-specific gene. The SOS boxes lay in the respective promoter regions of the genes that they regulated.

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2002-11-01
2020-12-01
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