1887

Abstract

Amplified fragment length polymorphism (AFLP) genotyping of isolates of the pathogenic fungus suggested a considerable genetic divergence between the varieties var. and var. on the one hand versus var on the other. This divergence is supported by additional phenotypic, biochemical, clinical and molecular differences. Therefore, the authors propose the existence of two species, (Sanfelice) Vuillemin and Kwon-Chung, which differ in geographical distribution, serotypes and ecological origin. Within each species three AFLP genotypes occur, which differ in geographical distribution and serotypes. Differences in ecological origin (AIDS patients, non-AIDS patients, animals or the environment) were found to be statistically not significant. In as well as in one of the genotypes represented a hybrid. The occurrence of hybridization has consequences for the reproductive biology of the species, as new genotypes with altered virulence or susceptibility to antifungal drugs may arise through the exchange of genetic material.

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2001-04-01
2020-01-23
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