1887

Abstract

The enantioselective reduction of racemic sulfoxides by dimethyl sulfoxide reductases from and was investigated. Purified dimethyl sulfoxide reductase from catalysed the selective removal of -methyl -tolyl sulfoxide from a racemic mixture of methyl -tolyl sulfoxide and resulted in an 88% recovery of enantiomerically pure -methyl -tolyl sulfoxide. was shown to be able to grow photoheterotrophically in the presence of certain chiral sulfoxides under conditions where a sulfoxide is needed as an electron sink. Whole cells of were shown to catalyse the enantioselective reduction of methyl -tolyl sulfoxide, ethyl 2-pyridyl sulfoxide, methylthiomethyl methyl sulfoxide and methoxymethyl phenyl sulfoxide. Similarly, whole cells of and reduced these sulfoxides but with opposite enantioselectivity.

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/content/journal/micro/10.1099/00221287-144-8-2247
1998-08-01
2019-10-14
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-144-8-2247
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