Adenosylcobalamin-dependent methylmalonyl-CoA mutase isozymes in the photosynthetic protozoon Free

Abstract

The photosynthetic protozoon Z contains adenosylcobalamin-dependent methylmalonyl-CoA mutase (MCM) involved in propionate metabolism. The specific activity of the mutase was about 6·5-fold greater in propionate-adapted cells than in photoautotrophic cells (control). Although the control cells contained only one mutase (apparent 72000), the propionate-adapted cells contained two mutases with values of 72000 and 17000; both enzymes were located in the mitochondria. These results provide evidence that propionate-adapted contains two MCM isozymes. The induced mutase ( 17000) permits photoassimilation of propionate.

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1996-09-01
2024-03-28
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