1887

Abstract

SUMMARY: The sensitizing effect and the local and general toxicity related to membrane components of the archaeobacterium was studied. Cell envelope fragments were biologically active but this activity was lost upon separation of the lipid and protein components. The envelope fragments exerted lethal effects on mice sensitized with D-galactosamine that were prevented by pretreatment with anti-TNF-α serum. This lethal activity occurred in both LPS-responder (BALB/cByJ) and LPS-nonresponder (C3H/HeJ) mouse strains. In addition, envelope fragments tested in rabbits caused a local Shwartzman reaction, and showed pyrogenic activity. , the envelope fragments that act on spleen lymphocytes of the LPS-responder (BALB/cByJ) and LPS-nonresponder (C3H/HeJ) mice caused an uptake of [H]thymidine similar to that caused by concanavalin A. A similar toxic activity to that exerted by eubacteria is therefore exerted by this non-pathogenic archaeobacterium despite the difference in surface chemistry.

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1993-09-01
2021-05-16
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References

  1. Beutler B., Milsek I.W., Cerunt A. 1985; Passive immunization against cachectin/tumor necrosisfactor (TNF) protects mice from the lethal effect of endotoxin.. Science 229:869–871
    [Google Scholar]
  2. Brock T.D. 1978 Thermophilic Microorganisms and Life at High Temperatures, pp. 117–179 New York: Springer.;
    [Google Scholar]
  3. Brock T.D., Brock K.M., Belly R.T., Weiss R.L. 1972; Sulfolobus: a new genus of sulfur-oxidizing bacteria living at low pH and high temperature.. Archiv für Mikrobiologie 84:54–68
    [Google Scholar]
  4. Coran A. 1972; The intravenous use of fat for the total parenteral nutrition of the infant.. Lipids 7:455–457
    [Google Scholar]
  5. De rosa M., Gambacorta A. 1988; The lipids of archaebacteria.. Progress in Lipid Research 27:153–175
    [Google Scholar]
  6. Dubois M., Gilles K.A., Hamilton J.K., Rebers P.A., Smith F. 1956; Colorimetric method for determination of sugars and related substances.. Analytical Chemistry 28:350–356
    [Google Scholar]
  7. Freudenberg M.A., Galanos C. 1988; Induction of tolerance to (LPS)-D-galactosamine lethality by pretreatment with LPS is mediated by macrophages.. Infection and Immunity 56:1352–1357
    [Google Scholar]
  8. Freudenberg M.A., Galanos C. 1991; Tumor necrosis factor alpha mediated lethal activity of killed Gram-negative and Grampositive bacteria in D-galactosamine treated mice. Infection and Immunity 59:2110–2115
    [Google Scholar]
  9. Freudenberg M.A., Keppler P., Galanos C. 1986; Requirement for lipopolysaccharide responsive macrophages in galactosamine-induced sensitization to endotoxin.. Infection and Immunity 51:891–895
    [Google Scholar]
  10. Galanos C., Freudenberg M.A., Reutter W. 1979; Galactosamine induced sensitization to the lethal effects of endotoxin.. Proceedings of the National Academy Sciences of the United States of America 76:5939–5943
    [Google Scholar]
  11. Galdiero F., Tufano M.A., Sommese L., Folgore A., Tedesco F. 1984; Activation of complement system by porins extracted from Salmonella typhimurium. . Infection and Immunity 46:559–563
    [Google Scholar]
  12. Galdiero F., Tufano M.A., Galdiero M., Masiello S., Dirosa M. 1990; Inflammatory effects on Salmonella typhimurium porins.. Infection and Immunity 58:3183–3186
    [Google Scholar]
  13. Galdiero F., Romano Carratelli C., Bentiviglio C., Capasso C., Ciofei S., Folgore A., Gorga F., Ianniello R., Mattera S., Nuzzo I., Rizzo A., Tufano M.A. 1991; Correlation between modification of membrane phospholipids and some biological activity of lymphocytes, neutrophils and macrophages.. Immuno-pharmacology and Immunotoxicology 13:623–642
    [Google Scholar]
  14. Iribe H, Koga T., Onoue K., Kotani S., Kusumoto S., Shiba T. 1981; Macrophage-stimulating effect of a synthetic muramyl-dipeptide and its adjuvant-active and inactive analogs for the production of the cell-activating monokines.. Cellular Immunology 64:73–77
    [Google Scholar]
  15. Laemmli U.K. 1970; Cleavage of structural proteins during the assembly of the head of bacteriophage T4.. Nature: London; 227680–685
    [Google Scholar]
  16. Lehmann V, Freudenberg M.A., Galanos C. 1987; Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine treated mice.. Journal of Experimental Medicine 165:657–663
    [Google Scholar]
  17. Mangan D.F, Wahl S.M., Sultzer B.M., Mergenhagen S.E. 1992; Stimulation of human monocytes by endotoxin-associated protein: inhibition of programmed cell death (apoptosis) and potential significance in adjuvanticity.. Infection and Immunity 60:1684–1686
    [Google Scholar]
  18. Munson T.E. 1985; Structure, biomedical significance and detection withthe Limulus Amebocyte Lysate test.. In Bacterial Endotoxins pp. 211–220 ten Cate J.W., Buller H.R., Sturk A. Edited by New York: Academic Press.;
    [Google Scholar]
  19. Nicolaus B., Trincone A., Esposito E., Vaccaro M.R., Gambacorta A, De Rosa M. 1990; Calditol tetraether lipids of the archaebacterium Sulfolobus solfataricus. . Biochemical Journal 266:785–791
    [Google Scholar]
  20. Oppenheim J.L, Togawa A., Chedid L., Mizel S. 1980; Components of mycobacteria and muramyl dipeptide with adjuvant activity induce lymphocyte activating factor.. Cellular Immunology 50:71–74
    [Google Scholar]
  21. Rosenstreich D.L. 1985; Genetic control of endotoxin response: C3H/HeJ mice.. In Handbook of Endotoxins 3 pp. 82–122 Berry L.J. Edited by New York: Elsevier;
    [Google Scholar]
  22. Selye H., Tuchweber B., Bertok L. 1966; Effect of lead acetate on the susceptibility of rats to bacterial endotoxins.. Journal of Bacteriology 91:884–890
    [Google Scholar]
  23. Seyberth H.W., Schmidt-Gay K.H., Hackethal E. 1972; Toxicity clearance and distribution of endotoxin in mice as influenced by actinomycin D, cycloheximide, ɑ-amanitinand lead acetate.. Toxicon 10:491–500
    [Google Scholar]
  24. Sultzer B.M., Craig J.P., Castagna R. 1986; Endotoxin associated proteins and their polyclonal and adjuvant activities.. In Immunobiology and Immunopharmacology of Bacterial Endotoxins pp. 435–447 Szentivanyi A., Friedman H. Edited by New York: Plenum;
    [Google Scholar]
  25. Taylor K.A., Deatherage J.F., Amos L.A. 1982; Structure of the S-layer of Sulfolobus acidocaldarius. . Nature; London: 299840–842
    [Google Scholar]
  26. Thye Yin E., Galanos C., Kinsky S., Bradshaw R.A., Wessler 5., Luderity O., Sarmiento M.F. 1972; Picogram sensitive assay for endotoxin : gelation of Limulus polyphemus blood cell lysate induced by purified lipopolysaccharide and lipid A from Gramnegative bacteria.. Biochimica et Biophysica Acta 261:284–289
    [Google Scholar]
  27. Tsai C.M., Frasch C.E. 1982; A sensitive silver-stain for detecting lipopolysaccharides in polyacrylamide gels.. Analytical Biochemistry 119:115–119
    [Google Scholar]
  28. Tuomanen E., Rich R., Zak O. 1987; Induction of pulmonary inflammation by components of the pneumococcal cell surface.. American Reviews of Respiratory Disease 135:869–873
    [Google Scholar]
  29. Wassef N.M., Alving C.R. 1987; Modulation of phosphatidylinositol turnover by liposomes containing phosphatidylinositol.. Methods in Enzymology 141:244–255
    [Google Scholar]
  30. Wardle E.N. 1979; Bacteraemic and endotoxic shock.. British Journal of Hospital Medicine 21:223–231
    [Google Scholar]
  31. Weiss R.L. 1974; Subunit cell wall of Sulfolobus acidocaldarius. . Journal of Bacteriology 118:275–284
    [Google Scholar]
  32. Yamamoto A., Usami H., Nagamuta M., Sugawara Y., Hamada 5., Yamamoto T., Kato K., Kokeguki S., Kotani S. 1985; The use of lipoteichoic (LTA) from Streptococcus pyogenes to induce a serum factor causing tumor necrosis.. British Journal of Cancer 51:739–745
    [Google Scholar]
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