RT Journal Article SR Electronic(1) A1 Krüger, Steffen A1 Stülke, Jörg A1 Hecker, MichaelYR 1993 T1 Catabolite repression of β-glucanase synthesis in Bacillus subtilis JF Microbiology, VO 139 IS 9 SP 2047 OP 2054 DO https://doi.org/10.1099/00221287-139-9-2047 PB Microbiology Society, SN 1465-2080, AB SUMMARY: β-Glucanase synthesis in Bacillus subtilis was repressed by glucose and other substrates of glycolysis. Experiments with different pts mutants showed that the phosphoenolpyruvate:sugar phosphotransferase system is not involved in carbon catabolite repression of β-glucanase synthesis. Carbon catabolite repression of β-glucanase synthesis was completely abolished in a ccpA mutant. An operator structure similar to those upstream of amyE and the xyl operon was found and was shown by site-directed mutagenesis to be the target for carbon catabolite repression of β-glucanase synthesis. The presence of this operator on a multi-copy plasmid resulted in a reduced repression of both β-glucanase and α-amylase synthesis. It seems likely that the gene encoding these enzymes are part of one regulon with respect to catabolite repression., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-139-9-2047