SUMMARY: A temperature-sensitive mutation in a new gene, located at 62.5 min on the linkage map and designated resulted in bacteriolysis at the restrictive temperature. Temperature sensitivity and -mediated lysis were simultaneously suppressed by either of two previously described unlinked mutations designated and The and alleles were originally isolated as specific extragenic suppressors of temperature-sensitive mutations in three other genes known as (99 min), (13 min) and (25 min) which conferred lysis phenotypes indistinguishable from that of the mutation. The and genes have been proposed to be related on the bases of phenotypic similarities and the specificities of their extragenic suppressors. It is now further proposed that belongs to this group. The isolation of new alleles of and as extragenic suppressors of further supports this proposal.


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