1887

Abstract

Macrophage (MΦ) chemiluminescence (CL) induced by interaction with the two types of colonial variants of was studied. A smooth, opaque and dome-shaped (SmD) colonial variant triggered more intense MΦ CL than did a smooth, transparent and flat colonial variant (SmT). MΦ CL-inducing activity of the SmD variant was reduced by heating or by treatments with either Pronase P, some endoglycosidases or Tween 80, thereby indicating that the SmD variant possesses MΦ CL-inducing substance(s) having peptide, sugar and/or lipid-like moieties. Treatment of the SmD variant organism with some endoglycosidases, such as cellulase, pectinase, dextranase or α-amylase decreased its MΦ CL-inducing ability. On the other hand, MΦ CL-inducing activity of the SmT variant was not affected by any of above treatments except that it was slightly increased by Pronase P treatment and reduced by α-amylase and dextranase.

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1993-12-01
2024-04-25
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References

  1. Adams L.B., Hibbs J.B.Jr Krahenbuhl J.L. 1990; Micro biostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from arginine. Journal of Immunology 144:2725–2729
    [Google Scholar]
  2. Dhariwal K.R., Liav L.A., Vatter A.E., Dhariwal G., Goren M.B. 1986; Haptenic oligosaccharides in antigenic variants of mycobacterial C-mycosides antagonize lipid receptor activity for mycobacteriophage D4 by masking a methylated rhamnose. Journal of Bacteriology 168:283–293
    [Google Scholar]
  3. Dorfman A. 1955; Mucopolysaccharidases. Methods in Enzymology 1:166–173
    [Google Scholar]
  4. Flesch I.A., Kaufmann S.H. 1991; Mechanisms involved in mycobacterial growth inhibition by gamma interferon-activated bone marrow macrophages: role of reactive nitrogen intermediates. Infection and Immunity 59:3213–3218
    [Google Scholar]
  5. Fukumoto J., Tsuji H., Tsuru D. 1971; Studies on mold dextranase. Penicillium luteum dextranase: its production and some enzymatic properties. Journal of Biochemistry 69:1113–1121
    [Google Scholar]
  6. Gangadharam P.R.J., Edwards C.K.III 1984; Release of superoxide anion from resident and activated mouse peritoneal macrophages infected with Mycobacterium intracellulare. American Review of Respiratory Disease 130:834–838
    [Google Scholar]
  7. Goto Y., Nakamura R., Takahashi H., Tokunaga T. 1984; Genetic control of resistance to Mycobacterium intracellulare infection in mice. Infection and Immunity 46:135–140
    [Google Scholar]
  8. Johnston R.B.Jr 1978; Oxygen metabolism and microbicidal activity of macrophages. Federation Proceedings 372759–2764
    [Google Scholar]
  9. Kertesz I. 1955; Pectic Enzymes. Methods in Enzymology 1:158–166
    [Google Scholar]
  10. Liew F.Y., Millot S., Parkinson C., Palmer R.M., Moncada S. 1990; Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from l-arginine. Journal of Immunology 144:4794–4797
    [Google Scholar]
  11. Mercier C., Frantz B.M., Whelan W.J. 1972; An improved purification of cell-bound pullulanase from Aerobacter aerogenes. European Journal of Biochemistry 26:1–9
    [Google Scholar]
  12. Moore A.E., Stone B.A. 1972; A β-l,3-glucan hydrolase from Nicotiana glutinosa. I. Extraction purification and physical properties. Biochimica et Biophysica Acta 258:238–247
    [Google Scholar]
  13. Nishizawa K., Kanda T., Shikata S., Wakabayashi K. 1978; Modulation of hydrolysis products by different types of exo-cellulases from Trichoderma viride. Journal of Biochemistry 83:1625–1630
    [Google Scholar]
  14. Ofek I., Sharon N. 1988; Lectinophagocytosis: a molecular mechanism of recognition between cell surface sugars and lectins in the phagocytosis of bacteria. Infection and Immunity 56:539–547
    [Google Scholar]
  15. Ogawa T., Saba K. 1949; The quantitative culture method for tubercle bacilli: on the case of cultivation of bacterial suspension. Kekkaku 24:13–18
    [Google Scholar]
  16. Park J., Rikihisa Y. 1992; l-Arginine-dependent killing of intracellular Ehrlichia risticii by macrophages treated with gamma interferon. Infection and Immunity 60:3504–3508
    [Google Scholar]
  17. Saito H., Tomioka H. 1988; Susceptibilities of transparent, opaque and rough colonial variants of Mycobacterium avium complex to various fatty acids. Antimicrobial Agents and Chemotherapy 32:400–402
    [Google Scholar]
  18. Saito H., Tomioka H. 1990; The role of macrophages in host defence mechanisms against Mycobacterium avium complex infection induced in mice. Research in Microbiology 141:206–212
    [Google Scholar]
  19. Schaefer W.B., Davis C.L., Cohn M.L. 1970; Pathogenicity of transparent, opaque, and rough variants of Mycobacterium avium in chickens and mice. American Review of Respiratory Disease 102:499–506
    [Google Scholar]
  20. Skamene E. 1989; Genetic control of susceptibility to mycobacterial infections. Reviews of Infectious Disease 11:S394–S399
    [Google Scholar]
  21. Thoma J.A., Spradlin J.E., Dygert S. 1971; Plant and animal amylases. In The Enzyme 5 pp. 115–118 Boyer P. D. Edited by New York: Academic Press;
    [Google Scholar]
  22. Tomioka H., Sato K., Saito H. 1992; Relationship between virulence to mice and macrophage chemiluminescence-triggering activity of the Mycobacterium avium complex belonging various serovars. Kekkaku 67:1–8 in Japanese
    [Google Scholar]
  23. Woodley C.L., David H.L. 1976; Effect of temperature on the rate of the transparent to opaque colony type transition in Mycobacterium avium. Antimicrobial Agents and Chemotherapy 9:113–119
    [Google Scholar]
  24. Yamada Y., Saito H., Tomioka H., Jidoi J. 1987; Relationship between the susceptibility of various bacteria to active oxygen species and to intracellular killing by macrophages. Journal of General Microbiology 133:2015–2021
    [Google Scholar]
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