1887

Abstract

SUMMARY: The aetiological agents of Lyme disease form a phylogenetically heterogeneous group, composed of three species, and group VS461. We have compared the sizes of the linear plasmid that carries the genes encoding the major outer-surface proteins OspA and OspB as well as the size and structure of the chromosome among the Lyme disease spirochaetes. We have found differences in the sizes of the -containing plasmids, but not the linear chromosomes among the three species. The -containing plasmid size of 50 kb in isolates is significantly smaller than the size of 55 kb in isolates and 56 kb in group VS461 isolates. The chromosome was found to be linear in all three species, but not significantly different in size.

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1993-10-01
2021-07-30
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