%0 Journal Article %A Woodward, S. %A Sultan, H. Y. %A Barrett, D. K. %A Pearce, R. B. %T Two new antifungal metabolites produced by Sparassis crispa in culture and in decayed trees %D 1993 %J Microbiology, %V 139 %N 1 %P 153-159 %@ 1465-2080 %R https://doi.org/10.1099/00221287-139-1-153 %I Microbiology Society, %X The basidiomycete fungus Sparassis crispa produced three antifungal compounds during submerged culture in 2% malt broth. One compound appeared to be sparassol (methyl-2-hydroxy-4-methoxy-6-methylbenzoate), first characterized in 1924. The other two, termed ScI and ScII, exhibited considerably greater antifungal activity than did sparassol against Cladosporium cucumerinum, and were characterized as methyl-2,4-dihydroxy-6-methylbenzoate (methyl orsellinate) and an incompletely determined methyl-dihydroxy-methoxy-methylbenzoate, respectively. Both compounds were found in the decayed wood of trees, where their presence was diagnostic of S. crispa infection. The possible ecological role of these compounds is discussed. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-139-1-153