1887

Abstract

The basidiomycete fungus produced three antifungal compounds during submerged culture in 2% malt broth. One compound appeared to be sparassol (methyl-2-hydroxy-4-methoxy-6-methylbenzoate), first characterized in 1924. The other two, termed ScI and ScII, exhibited considerably greater antifungal activity than did sparassol against , and were characterized as methyl-2,4-dihydroxy-6-methylbenzoate (methyl orsellinate) and an incompletely determined methyl-dihydroxy-methoxy-methylbenzoate, respectively. Both compounds were found in the decayed wood of trees, where their presence was diagnostic of infection. The possible ecological role of these compounds is discussed.

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1993-01-01
2021-05-13
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References

  1. Barrett D.K. 1985; Basidiospores of Phaeolus schweinitzii: a source of soil infestation. European Journal of Forest Pathology 15:417–425
    [Google Scholar]
  2. Brian P.W. 1951; Antibiotics produced by fungi. Botanical Review 17:357–430
    [Google Scholar]
  3. Broadbent D. 1968; Antibiotics produced by fungi. Pest Articles and News Summaries 14:120–141
    [Google Scholar]
  4. Cwielong P. 1986 Mechanismen der Resistenz und der Pathogenitat von fungizid wirksamen Naturstoffen gegenuber dem Erreger der Rotfäule Heterobasidion annosum (Fr.)Bref PhD dissertation Universität Göttingen, Germany.:
    [Google Scholar]
  5. Donnelly D., Sanada S., O’Reilly J., Polonsky J., Prangé T., Pascard C. 1982; Isolation and structure (X-ray analysis) of the orScIIinate of armillol, a new antibacterial metabolite from Armillaria mellea. Journal of the Chemical Society. Chemical Communications 1982135–137
    [Google Scholar]
  6. Donnelly D.M. X., Polonsky J., Prangé T., Snatzke G., Wagner U. 1984; The absolute configuration of the orScIIinate of armillol: application of the coupled oscillator theory. Journal of the Chemical Society. Chemical Communications 1984222–223
    [Google Scholar]
  7. Donnelly D. M. X., O’Reilly J., Polonsky J., Sheridan M.H. 1987; In vitro production and biosynthesis of fomajorin D and S by Fomes annosus (Fr.) Cooke. Journal of the Chemical Society. Perkin Transactions 19871869–1872
    [Google Scholar]
  8. Falck R. 1923; Über ein krystalliscertes Stoffwechsel produkt von Sparassis ramosa Schaff. Berichte der Deutschen Chemischen GeScIIschaft (Berlin) 56:2555–2556
    [Google Scholar]
  9. Fisher P.J., Anson A.E. 1983; Antifungal effects of Massarina aquatica growing on oak wood. Transactions of the British Mycological Society 81:523–527
    [Google Scholar]
  10. Fujikawa F., Hitosa Y., Yagi Y., Yasuda K. 1956; Antiseptics for foodstuff. LX. Yakugaka Zasshi 76:674–678
    [Google Scholar]
  11. Fujikawa F., Hirayama T., Nakamura Y., Suzuki M., Doi M., Niki C. 1970; Studies for antiseptics for foodstuff. LXXI. Studies on orScIIinic acid ester, p-orcinolcarboxylic acid ester and olivetonide as a preservative for saki. Yakugaka Zasshi 90:1517–1519
    [Google Scholar]
  12. Gramss G. 1987; The influence of the concomitant microflora on establishment and dieback of decay fungi in standing timber. Journal of Phytopathology 120:205–215
    [Google Scholar]
  13. Hervey A.H. 1947; A survey of 500 basidiomycetes for antibacterial activity. Bulletin of the Torrey Botanical Club 74:476–503
    [Google Scholar]
  14. Homans A.L., Fuchs A. 1970; Direct bioautography on thin layer chromatograms as a method for detecting fungitoxic substances. Journal of Chromatography 51:327–329
    [Google Scholar]
  15. Hüttermann A. 1987; History of forest botany (Forstbotanik) in Germany from the beginning in 1800 until 1940 - Science in the tension field between university and professional responsibility. Berichte der deutschen botanische GeScIIschaft 100:107–141
    [Google Scholar]
  16. Last F.T., Hanley R.E. 1956; A local lesion technique for measuring the infectivity of conidia of Botrytis fabae Sardiña. Annals of Applied Biology 44:410–418
    [Google Scholar]
  17. Lennartz T. 1947; Über antituberkulöse Stoffe: Antibiosche Eigenschaften von Derivaten des Orcins. Zeitschrift fur Naturforschung 2B:7–9
    [Google Scholar]
  18. Mathieson J. 1946; Antibiotics from Victorian basidiomycetes. Australian Journal of Experimental Biologv and Medical Science 24:57–62
    [Google Scholar]
  19. Medland S.L., Izak R.R., Wing R.M., Zaki A.I., Munnixxe D.E., Sims J.J. 1982; Melleolide, a new antibiotic from Armillaria mellea. Tetrahedron Letters 23:2515–2518
    [Google Scholar]
  20. Phillips D.H., Burdekin D.A. 1982 Diseases of Forest and Ornamental Trees London: Macmillan.:
    [Google Scholar]
  21. Rayner A.D.M., Boddy L. 1988 Fungal Decomposition of Wood Chichester: John Wiley:
    [Google Scholar]
  22. Robbins W.J., Hervey A., Davidson R.W., Ma R., Robbins W.C. 1945; A survey of some wood-destroying and other fungi for antibacterial activity. Bulletin of the Torrey Botanical Club 72:165–190
    [Google Scholar]
  23. Rossall S., Mansfield J.W. 1978; The activity of wyeronc acid against Botrytis. Annals of Applied Biology 89:359–362
    [Google Scholar]
  24. Siepmann R. 1987; Wachstumshemmung von Stammfaulepilzen und von Gremmeniella abietina durch Bacillus subtilis. European Journal of Forest Pathology 17:59–64
    [Google Scholar]
  25. Sonnenbichler J., Blieste I. M., Peipp H., Holdenrieder O. 1989; Secondary fungal metabolites and their biological activities. I. Isolation of antibiotic compounds from cultures of Heterobasidion annosum synthesized in the presence of antagonistic fungi or host plant cells. Biological Chemistry Hoppe-Seyler 370:1295–1303
    [Google Scholar]
  26. Stalpers J.A. 1978; Identification of wood-inhabiting fungi in pure culture. Studies in Mycology 16 Baarn:Centraalbureau voor Schimmelcultures:
    [Google Scholar]
  27. Wedekind E., Fleischer K. 1923; Über die Konstitution des Sparassols. Berichte der deutschen chemischen GeScIIschaft 56:2556–2563
    [Google Scholar]
  28. Wedekind E., Fleischer K. 1924; Zur Kenntnis des Sparassols. Berichte der deutschen chemischen GeScIIschaft 57: (Abt. B) 1121–1123
    [Google Scholar]
  29. Wilkins W. H. 1945; Investigation into the production of bacteriostatic substances by fungi. Cultural work on basidiomycetes. Transactions of the British Mycological Society 28:110–114
    [Google Scholar]
  30. Wilkins W. H. 1946; Investigation into the production of bacteriostatic substances by fungi: preliminary examination of the fifth 100 species, all basidiomycetes, mostly of the wood-destroying type. British Journal of Experimental Pathology 27:140–142
    [Google Scholar]
  31. Wilkins W. H., Harris G. C. M. 1944; Investigation into the production of bacteriostatic substances by fungi. VI. Examination of the larger basidiomycetes. Annals of Applied Biology 31:261–270
    [Google Scholar]
  32. Woodward S., Pearce R. B. 1988; The role of stilbenes in resistance of Sitka spruce (Picea sitchensis (Bong.) Carr.) to entry of fungal pathogens. Physiological and Molecular Plant Pathology 33:127–149
    [Google Scholar]
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