@article{mbs:/content/journal/micro/10.1099/00221287-138-9-1797, author = "Connerton, I. F. and McCullough, W. and Fincham, J. R. S.", title = "An acetate-sensitive mutant of Neurospora crassa deficient in acetyl-CoA hydrolase", journal= "Microbiology", year = "1992", volume = "138", number = "9", pages = "1797-1800", doi = "https://doi.org/10.1099/00221287-138-9-1797", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-138-9-1797", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "The predicted amino acid sequence of the product of the acetate-inducible acu-8 gene of Neurospora crassa, previously of unknown function, has close homology to the recently published sequence of Saccharomyces cerevisiae acetyl-CoA hydrolase. An acu-8 mutant strain, previously characterized as acetate non-utilizing, shows strong growth-inhibition by acetate, but will use it as carbon source at low concentrations. The mutant was shown to be deficient in acetyl-CoA hydrolase and to accumulate acetyl-CoA when supplied with acetate. As in Saccharomyces, the Neurospora enzyme is acetate-inducible.", }