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Volume 138, Issue 9

An acetate-sensitive mutant of deficient in acetyl-CoA hydrolase Free

Abstract

The predicted amino acid sequence of the product of the acetate-inducible gene of , previously of unknown function, has close homology to the recently published sequence of acetyl-CoA hydrolase. An mutant strain, previously characterized as acetate non-utilizing, shows strong growth-inhibition by acetate, but will use it as carbon source at low concentrations. The mutant was shown to be deficient in acetyl-CoA hydrolase and to accumulate acetyl-CoA when supplied with acetate. As in , the enzyme is acetate-inducible.

  • Received:
  • Accepted:
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  • Published Online:
© Society for General Microbiology, 1992
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1992-09-01
2025-04-25
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/content/journal/micro/10.1099/00221287-138-9-1797
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An acetate-sensitive mutant of Neurospora crassa deficient in acetyl-CoA hydrolase
Microbiology 138, 1797 (1992); https://doi.org/10.1099/00221287-138-9-1797
/content/journal/micro/10.1099/00221287-138-9-1797
/content/journal/micro/10.1099/00221287-138-9-1797
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