@article{mbs:/content/journal/micro/10.1099/00221287-138-7-1345, author = "Riley, Margaret A. and Gordon, David M.", title = "A survey of Col plasmids in natural isolates of Escherichia coli and an investigation into the stability of Col-plasmid lineages", journal= "Microbiology", year = "1992", volume = "138", number = "7", pages = "1345-1352", doi = "https://doi.org/10.1099/00221287-138-7-1345", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-138-7-1345", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "A survey of colicins in the ECOR reference collection of Escherichia coli is presented. Twenty-five of the 72 ECOR strains exhibited a phenotype consistent with colicin production and E. coli isolated from human hosts were more likely to be colicinogenic than those from animal hosts. Multiple representatives of two Col plasmids, lowmolecular-mass ColE1 plasmids and high-molecular-mass, conjugative ColIa plasmids were isolated from the ECOR collection and were examined with a combination of restriction fragment and Southern analysis. These data suggested that ColE1 plasmids comprise a stable (cohesive) plasmid lineage, while ColIa plasmids represent a family of distinct plasmid lineages united by the presence of the colicin Ia operon.", }