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SUMMARY: The gene nagC encodes the repressor for the nag regulon. A point mutation within the gene, which confers a superrepressor phenotype and makes the repressor insensitive to the inducer, N-acetylglucosamine 6-phosphate, has been characterized. The mutation is semi-dominant since heterozygous diploids have reduced growth rates on glucosamine and N-acetylglucosamine compared to the wild-type strain.