%0 Journal Article %A Völker, Uwe %A Mach, Hiltraut %A Schmid, Roland %A Hecker, Michael %T Stress proteins and cross-protection by heat shock and salt stress in Bacillus subtilis %D 1992 %J Microbiology, %V 138 %N 10 %P 2125-2135 %@ 1465-2080 %R https://doi.org/10.1099/00221287-138-10-2125 %I Microbiology Society, %X Bacillus subtilis induced a set of general stress proteins in response to a salt or heat stress. Cells subjected to a mild heat stress showed a protective response which enabled them to survive otherwise lethal temperatures (e.g. 52 °C). In a similar way bacteria were enabled to survive toxic concentrations of NaCl by pretreatment with lower salt concentrations. A mild heat shock induced a cross-protection against lethal salt stress. The pretreatment of cells with low salt, however, was less effective in the induction of thermotolerance than a preceding mild heat stress. Three stress proteins were identified on the basis of their N-terminal amino acid sequences as homologues of GroEL, DnaK and ClpP of Escherichia coli. The role of general and specific stress proteins in the induction of thermotolerance/salt tolerance and cross-protection is discussed. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-138-10-2125