mutants with null mutations in the gene are resistant to oxidative stress during the exponential phase of growth. This resistance phenotype can be suppressed by mutations in the gene, or in the gene. Both of these gene products are negative regulatory proteins which are over-produced in a strain, and the over-production of the gene product results from over-production of the gene product. The results suggested that the resistance to oxidative stress in a strain is due to the lack of a protein directly controlled by the negative regulator. Other mutations in the gene conferring resistance to ethanol stress () or suppressors of sporulation phenotypes () had no effect on the sensitivity to oxidative stress of strains bearing them.


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