1887

Abstract

Summary: The effects of subminimal inhibitory concentrations (subMICs) of certain antibiotics, namely penicillin G, tetracycline and trimethoprim/sulphamethoxazole, on the growth and morphology of were evaluated. SubMICs of penicillin markedly reduced the growth of Tetracycline and trimethoprim/ sulphamethoxazole had no effect on its growth. SubMICs of penicillin greatly affected the morphology of At the highest concentrations tested (1/2 and 1/4 MIC) cells were acapsulate, and long filamentous cells (4–6 μm) were observed with some isolates. There was no correlation between the observed differences in the penicillin-binding proteins of the isolates, and the extent of cell filamentation induced by penicillin G. SubMICs of tetracycline and trimethoprim/sulphamethoxazole did not seem to affect capsule production although filamentation was observed. Our results indicate that subMICs of penicillin can reduce growth of Furthermore, results also indicate that subMICs of antibiotics can affect the production of capsular material and the morphology of

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-137-11-2663
1991-11-01
2019-10-16
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-137-11-2663
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error