1887

Abstract

Summary: Genes for type b capsule expression are duplicated to form a potentially unstable structure, , of directly-repeated chromosomal regions of approximately 17 kb. Capsule-deficient mutants arise in a two-stage process, initiated by -dependent reduction of this region from two copies to one. This recombinational event is usually lethal, only about 1/200 surviving to form slow-growing colonies of organisms that continue to synthesize polysaccharide but are defective in its export. A variety of secondary ‘rescue’ mutations within can occur to reduce polysaccharide synthesis and restore normal organism appearance and colony morphology.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-137-11-2571
1991-11-01
2019-11-19
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-137-11-2571
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error